LUNG CANCER and cannabis studies completed
Overview
Lung cancer, also known as carcinoma of the lung or pulmonary carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
 
The medical science is strongly in favour of THC laden hemp oil as a primary cancer therapy, not just in a supportive role to control the side effects of chemotherapy.

There are three main types of lung cancer. Knowing which type you have is important because it affects your treatment options and your outlook (prognosis). If you aren’t sure which type of lung cancer you have, ask your doctor so you can get the right information.

Medical Cannabis:
THC has been found to reduce tumor growth in common lung cancer by 50 percent and to significantly reduce the ability of the cancer to spread, say researchers at Harvard University, who tested the chemical in both lab and mouse studies.
Science & Research
Video -Does Smoking Weed Cause Cancer?
Undated - Article - CLAIM #4: MARIJUANA CAUSES LUNG DISEASE.

2013 - Editorial ~ Cannabis and the Lung: No More Smoking Gun?

2013 - Study ~ COX-2 and PPAR-γ Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells.

2013 - Study ~ Effects of marijuana smoking on the lung.

2013 - Study ~ Cannabis smoking and lung cancer risk: pooled analysis in the International Lung Cancer Consortium

2013 - Study ~ Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells.

2013 - News ~ "Miracle" Cannabis Oil: May Treat Cancer, But Money and the Law Stand in the Way of Finding Out

2013 - News ~ Federal Government Reports Marijuana Effective in Combatting Certain Cancers Reports ADSI

2013 - News ~ Marijuana habit not linked to lung cancer

2012 - Study ~ Anti-proliferative and Anti-angiogenic Effects of CB2R Agonist (JWH-133) in Non-small Lung Cancer Cells (A549) and Human Umbilical Vein Endothelial Cells: an in Vitro Investigation.

2012 - Study ~ Association Between Marijuana Exposure and Pulmonary Function Over 20 Years

2012 - News ~ Marijuana compound could stop aggressive cancer metastasis

2012 - News ~ Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In
Aggressive Cancers

2012 - News ~ Can marijuana stop cancer?

2012 - News ~ Media Ignored Expert's Shocking Findings That Marijuana Helps Prevent Lung Cancer: Now It's Med-School Material

2012 - News ~ Is Marijuana the Cancer Cure We’ve Waited For?

2012 - News ~ Study: Smoking Marijuana Not Linked with Lung Damage

2011 - Study ~ Effects of smoking cannabis on lung function.

2011 - Study ~ Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis.

2011 - Study ~ Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.

2010 - Study ~ Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells.

2010 - Study ~ Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.

2008 - Letter ~ Doubts about the role of cannabis in causing lung cancer.

2008 - Study ~ Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1.

2008 - Study ~ Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo.

2007 - Study ~ {Delta}-9 Tetrahydrocannabinol inhibits growth and metastasis of lung cancer.

2007 - Study - Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo.

2007 - News - Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells.

2007 - News - Marijuana May Fight Lung Tumors.

2007 - News ~ Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows.

2007 - News ~ Pot's Active Ingredient Halts Lung Cancer Growth, Study Says.

2007 - News ~ Marijuana Helps to Combat Lung Cancer.

2007 - News ~ Cannabis as a possible treatment for lung cancer.

2007 - News ~ Marijuana Beneficial in Fighting Lung Tumors, Study.

2006 - News ~ Study Finds No Link Between Marijuana Use And Lung Cancer.

2006 - News ~ Study Finds No Cancer-Marijuana Connection.

2006 - News ~ No association between lung cancer and cannabis smoking in large study.

2006 - News ~ Pot Smoking Not Linked to Lung Cancer.

2006 - News ~ Large Study Finds No Link between Marijuana and Lung Cancer.

2006 - News ~ There Seems to Be No Link between Marijuana Use and Lung Cancer.

2005 - Study ~ Cannabis and tobacco smoke are not equally carcinogenic.

2005 - News - Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways.

2005 - News - No association between lung cancer and cannabis smoking in large study.

2005 - News ~ Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke.

2004 - Study - Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor {alpha}-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor.

2000 - Report - Anti-Tumor Effects.

1999 - News ~ So, you thought it was the tar that caused cancer.

1994 - News ~ Marijuana Less Harmful to Lungs than Cigarettes.

1992 - Study ~ No increase in carcinogen-DNA adducts in the lungs of monkeys exposed chronically to marijuana smoke.

1983 - Study ~ Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy.

1977 - Study ~ In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas.

1975 - Study - Anticancer activity of cannabinoids.

1975 - Study - Antineoplastic activity of cannabinoids.

Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
Preet A, Ganju RK, Groopman JE 
Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. [JOURNAL ARTICLE]
Oncogene 2007 Jul 9.

Delta(9)-Tetrahydrocannabinol (THC) is the primary cannabinoid of marijuana and has been shown to either potentiate or inhibit tumor growth, depending on the type of cancer and its pathogenesis. 

Little is known about the activity of cannabinoids like THC on epidermal growth factor receptor-overexpressing lung cancers, which are often highly aggressive and resistant to chemotherapy. 

In this study, we characterized the effects of THC on the EGF-induced growth and metastasis of human non-small cell lung cancer using the cell lines A549 and SW-1573 as in vitro models. 

We found that these cells express the cannabinoid receptors CB(1) and CB(2), known targets for THC action, and that THC inhibited EGF-induced growth, chemotaxis and chemoinvasion. Moreover, signaling studies indicated that THC may act by inhibiting the EGF-induced phosphorylation of ERK1/2, JNK1/2 and AKT.

THC also induced the phosphorylation of focal adhesion kinase at tyrosine 397. Additionally, in in vivo studies in severe combined immunodeficient mice, there was significant inhibition of the subcutaneous tumor growth and lung metastasis of A549 cells in THC-treated animals as compared to vehicle-treated controls. Tumor samples from THC-treated animals revealed antiproliferative and antiangiogenic effects of THC. 

Our study suggests that cannabinoids like THC should be explored as novel therapeutic molecules in controlling the growth and metastasis of certain lung cancers.Oncogene advance online publication, 9 July 2007; doi:10.1038/sj.onc.1210641